5 Essential Elements For phenobarbital sodium route of administration

5 Essential Elements For phenobarbital sodium route of administration

Blog Article

pentobarbital will lower the extent or effect of alprazolam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.

Monitor Carefully (two)pentobarbital will lower the extent or effect of buprenorphine, very long-performing injection by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Watch Intently. Patients who transfer to buprenorphine lengthy-acting injection from transmucosal buprenorphine coadministered with CYP3A4 inducers must be monitored to ensure buprenorphine plasma levels are suitable.

Contraindicated (one)pentobarbital will lower the level or effect of lonafarnib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Lonafarnib is really a sensitive CYP3A4 substrate. Coadministration with robust or moderate CYP3A4 inducers is contraindicated.

Contraindicated (one)pentobarbital will lower the extent or effect of roflumilast by impacting hepatic/intestinal enzyme CYP3A4 metabolism.

pentobarbital will lower the level or effect of abemaciclib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Coadministration of abemaciclib with strong CYP3A4 inducers minimizes plasma concentration of abemaciclib and its metabolites.

five. Standard lethal stage, the higher conclusion of the vary includes those that gained some supportive treatment.

pentobarbital will lower the level or effect of isradipine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Significance Unidentified.

Contraindicated (one)pentobarbital will lower the extent or effect of fostemsavir by affecting hepatic/intestinal enzyme CYP3A4 metabolism.

pentobarbital will decrease the extent or effect of doxorubicin by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.

Observe Intently (1)pentobarbital will enhance the level or effect of clopidogrel by click here affecting hepatic/intestinal enzyme CYP3A4 metabolism.

pentobarbital will reduce the level or effect of ramelteon by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Mysterious.

pentobarbital will lessen the extent or effect of rabeprazole by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Importance Not known.

pentobarbital will decrease the extent or effect of elbasvir/grazoprevir by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. The therapeutic effect of elbasvir/grazoprevir may be decreased if coadministered with solid CYP3A inducers and is particularly as a result contraindicated.

pentobarbital will reduce the extent or effect of alfuzosin by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Mysterious.